The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2013
Filed:
Mar. 06, 2009
Kazunori Kataoka, Tokyo, JP;
Nobuhiro Nishiyama, Tokyo, JP;
Atsushi Ishii, Tokyo, JP;
Yasuki Kato, Kashiwa, JP;
Kanjiro Miyata, Tokyo, JP;
Hyunjin Kim, Tokyo, JP;
Hiroyasu Takemoto, Tokyo, JP;
Kazunori Kataoka, Tokyo, JP;
Nobuhiro Nishiyama, Tokyo, JP;
Atsushi Ishii, Tokyo, JP;
Yasuki Kato, Kashiwa, JP;
Kanjiro Miyata, Tokyo, JP;
Hyunjin Kim, Tokyo, JP;
Hiroyasu Takemoto, Tokyo, JP;
The University of Tokyo, Tokyo, JP;
Abstract
The present invention relates to a block copolymer containing an uncharged hydrophilic polymer chain block and a cationic polyamino acid chain block, wherein the hydrophilic polymer chain block is covalently bound to one end of the main chain of the polyamino acid chain block, and the hydrophobic group is covalently bound to the side chains of not less than 10% and not greater than 70% of amino acid repeating units in the polyamino acid chain block. This block copolymer forms a stable aggregate with siRNA, a small-molecule nucleic acid, under a physiological condition.