The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2013

Filed:

Feb. 24, 2007
Applicants:

Derek O'hagan, Siena, IT;

Manmohan Singh, San Ramon, CA (US);

Janet Wendorf, Redwood City, CA (US);

Jina Kazzaz, San Rafael, CA (US);

Padma Malyala, Santa Clara, CA (US);

Inventors:

Derek O'Hagan, Siena, IT;

Manmohan Singh, San Ramon, CA (US);

Janet Wendorf, Redwood City, CA (US);

Jina Kazzaz, San Rafael, CA (US);

Padma Malyala, Santa Clara, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/12 (2006.01); A61K 39/02 (2006.01); A61K 39/002 (2006.01); A61K 39/21 (2006.01); A61K 39/29 (2006.01); A61K 39/145 (2006.01); A61K 39/10 (2006.01); A61K 39/05 (2006.01); A61K 39/08 (2006.01); A61P 37/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Immunogenic compositions are described herein which comprise microparticles that further comprise a biodegradable polymer. The microparticle compositions also comprise a cationic polysaccharide and an immunological species selected from an antigen, an immunological adjuvant and a combination thereof. Also described are methods of making such compositions and methods of administering such compositions. Methods of modulating the release rate of immunological species from microparticles are also described. These methods comprise varying the ratio of the cationic polysaccharide relative to the biodegradable polymer within the microparticles.


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