The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2013
Filed:
Oct. 01, 2008
Chul-hyun Park, Seongnam-si, KR;
Eun-ju Park, Seoul, KR;
Choong-hahn Kim, Seoul, KS (US);
Suk Man Jang, Yongin-si, KR;
Eun Jung Lim, Osan-si, KR;
Young Kil Chang, Seoul, KR;
Gwan Sun Lee, Seoul, KR;
Jaeheon Lee, Yongin-si, KR;
Chul-Hyun Park, Seongnam-si, KR;
Eun-Ju Park, Seoul, KR;
Choong-Hahn Kim, Seoul, KS (US);
Suk Man Jang, Yongin-si, KR;
Eun Jung Lim, Osan-si, KR;
Young Kil Chang, Seoul, KR;
Gwan Sun Lee, Seoul, KR;
Jaeheon Lee, Yongin-si, KR;
Hanmi Science Co., Ltd, Hwaseong-si, KR;
Abstract
The present invention relates to a method for preparing Montelukast acid or its sodium salt by reacting a thiol compound with a Montelukast intermediate in the presence of a base in a medium comprising an ionic liquid compound. In accordance with the inventive method, highly pure Montelukast acid or its sodium salt, which is advantageously used as a raw material in the preparation of Montelukast, a leukotriene antagonist, can be easily prepared in a high yield.