The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2013

Filed:

Aug. 04, 2005
Applicants:

Ellen Baxter, Glenside, PA (US);

Robert Boyd, Horsham, PA (US);

Steven J. Coats, McDonough, GA (US);

Alfonzo D. Jordan, North Wales, PA (US);

Allen B. Reitz, Lansdale, PA (US);

Charles H. Reynolds, Lansdale, PA (US);

Mark Schulz, Skippack, PA (US);

Malcolm Scott, Telford, PA (US);

Inventors:

Ellen Baxter, Glenside, PA (US);

Robert Boyd, Horsham, PA (US);

Steven J. Coats, McDonough, GA (US);

Alfonzo D. Jordan, North Wales, PA (US);

Allen B. Reitz, Lansdale, PA (US);

Charles H. Reynolds, Lansdale, PA (US);

Mark Schulz, Skippack, PA (US);

Malcolm Scott, Telford, PA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/88 (2006.01); C07D 239/94 (2006.01); C07D 401/06 (2006.01); A61K 31/535 (2006.01); C07D 265/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE.


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