The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2013
Filed:
May. 12, 2009
Masatomo Kato, Ikoma, JP;
Miwa Takai, Ikoma, JP;
Takahiro Matsuyama, Ikoma, JP;
Tatsuji Kurose, Ikoma, JP;
Yumi Hagiwara, Ikoma, JP;
Mamoru Matsuda, Ikoma, JP;
Toshiyuki Mori, Ikoma, JP;
Kenji Imoto, Ikoma, JP;
Atsuyoshi Dota, Ikoma, JP;
Masatomo Kato, Ikoma, JP;
Miwa Takai, Ikoma, JP;
Takahiro Matsuyama, Ikoma, JP;
Tatsuji Kurose, Ikoma, JP;
Yumi Hagiwara, Ikoma, JP;
Mamoru Matsuda, Ikoma, JP;
Toshiyuki Mori, Ikoma, JP;
Kenji Imoto, Ikoma, JP;
Atsuyoshi Dota, Ikoma, JP;
Santen Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
The present invention is related to glucocorticoid receptor agonists comprised of a compound represented by formula (1) which is 2,2,4-trimethyl-6-phenyl-1,2-dihydroquinoline derivative or a salt thereof and novel pharmacological effects of the glucocorticoid receptor agonists. In the formula (1), Rrepresents formula (2a), (3a), (4a) or (5a); R2 represents —(CO)—R8, —(CO)O—R9, or the like; R—O— is substituted at the 4- or -5-position of benzene ring A; Rrepresents a lower alkyl group; R, R, Ror Rrepresents a halogen atom, a lower alkyl group which may have a substituent, or the like; m, n, p or q represents 0, 1 or the like; R, Ror the like represents a lower alkyl group which may have a substituent, a lower alkenyl group, or the like.