The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2013

Filed:

May. 28, 2008
Applicants:

Zhaoning Zhu, Plainsboro, NJ (US);

William J. Greenlee, Teaneck, NJ (US);

Xianhai Huang, Warren, NJ (US);

Brian A. Mckittrick, New Vernon, NJ (US);

John W. Clader, Cranford, NJ (US);

Mark D. Mcbriar, Clinton, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Inventors:

Zhaoning Zhu, Plainsboro, NJ (US);

William J. Greenlee, Teaneck, NJ (US);

Xianhai Huang, Warren, NJ (US);

Brian A. McKittrick, New Vernon, NJ (US);

John W. Clader, Cranford, NJ (US);

Mark D. McBriar, Clinton, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5365 (2006.01); A61K 31/5395 (2006.01); C07D 498/04 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.


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