The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2013

Filed:

Jul. 23, 2010
Applicants:

Scott C. Weaver, Galveston, TX (US);

Ilya V. Frolov, Birmingham, AL (US);

Elena Frolova, Birmingham, AL (US);

Inventors:

Scott C. Weaver, Galveston, TX (US);

Ilya V. Frolov, Birmingham, AL (US);

Elena Frolova, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/04 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses an attenuated recombinant alphavirus that is incapable of replicating in mosquito cells and of transmission by mosquito vectors. These attenuated alphavirus may include but is not limited to Western Equine Encephalitis virus, Eastern equine encephalitis virus, Venezuelan equine encephalitis virus or Chikungunya virus. The present invention also discloses the method of generating such alphaviruses and their use as immunogenic compositions.


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