The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2013

Filed:

Dec. 26, 2007
Applicants:

Helen M. Blau, Menlo Park, CA (US);

Mark Morris Hammer, Gainesville, FL (US);

Tom Wehrman, Fremont, CA (US);

Inventors:

Helen M. Blau, Menlo Park, CA (US);

Mark Morris Hammer, Gainesville, FL (US);

Tom Wehrman, Fremont, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); C12Q 1/34 (2006.01); C12Q 1/68 (2006.01); C12N 5/00 (2006.01); C12N 1/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compositions for detecting the sub-cellular localization of a molecule are provided. Aspects of the invention include detecting translocation of a cell-surface receptor to a sub-cellular compartment, e.g., the endosome, using a reduced affinity enzyme complementation reporter system. Also provided are systems and kits for use in practicing embodiments of the methods.


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