The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2013
Filed:
Jun. 22, 2007
Haitao Wang, Vancouver, CA;
Chunsheng Mao, Vancouver, CA;
Jizhi LI, Vancouver, CA;
Ling Wang, Vancouver, CA;
Yong Du, Vancouver, CA;
Longbin Liu, West Vancouver, CA;
Jing Xu, Vancouver, CA;
Rui Zhang, Vancouver, CA;
Haitao Wang, Vancouver, CA;
Chunsheng Mao, Vancouver, CA;
Jizhi Li, Vancouver, CA;
Ling Wang, Vancouver, CA;
Yong Du, Vancouver, CA;
Longbin Liu, West Vancouver, CA;
Jing Xu, Vancouver, CA;
Rui Zhang, Vancouver, CA;
Novagen Holding Corporation, George Town, KY;
Abstract
This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID NO: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.