The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2013
Filed:
Jun. 04, 2009
Paul Lobben, Lawrenceville, NJ (US);
Rulin Zhao, Pennington, NJ (US);
Bei Wang, Yardley, PA (US);
Bang-chi Chen, Plainsboro, NJ (US);
Shuang Liu, Schenectady, NY (US);
Min HU, Schenectady, NY (US);
Yuh-lin Allen Yang, Slingerlands, NY (US);
Matthew Isherwood, Delmar, NY (US);
Rasidul Amin, East Greenbush, NY (US);
Wenge Cui, Clifton Park, NY (US);
Paul Lobben, Lawrenceville, NJ (US);
Rulin Zhao, Pennington, NJ (US);
Bei Wang, Yardley, PA (US);
Bang-Chi Chen, Plainsboro, NJ (US);
Shuang Liu, Schenectady, NY (US);
Min Hu, Schenectady, NY (US);
Yuh-Lin Allen Yang, Slingerlands, NY (US);
Matthew Isherwood, Delmar, NY (US);
Rasidul Amin, East Greenbush, NY (US);
Wenge Cui, Clifton Park, NY (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Albany Molecular Research, Inc., Albany, NY (US);
Abstract
Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form. One such intermediate has the following structure: