The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2013
Filed:
Sep. 11, 2003
Kozo Takeda, Tokyo, JP;
Norimichi Ochi, Tokyo, JP;
Kimie Ishii, Tokyo, JP;
Manabu Matsuhashi, Tokyo, JP;
Akinori Imamura, Tokyo, JP;
Kozo Takeda, Tokyo, JP;
Norimichi Ochi, Tokyo, JP;
Kimie Ishii, Tokyo, JP;
Manabu Matsuhashi, Tokyo, JP;
Akinori Imamura, Tokyo, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
A method is provided for purifying physiologically active proteins, especially antibodies, in order to remove impurities such as DNA contaminants and viruses with minimal loss of physiologically active proteins. The physiologically active protein is introduced into an aqueous solution of low conductivity at a pH of below the isoelectric point of the physiologically active protein to precipitate impurities as particles. The particles are removed, leaving a purified physiologically active protein.