The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

Apr. 27, 2005
Applicants:

Allan Weissman, Bethesda, MD (US);

Jennifer Mariano, Frederick, MD (US);

BO Chen, Frederick, MD (US);

Yien Che Tsai, Frederick, MD (US);

Inventors:

Allan Weissman, Bethesda, MD (US);

Jennifer Mariano, Frederick, MD (US);

Bo Chen, Frederick, MD (US);

Yien Che Tsai, Frederick, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention features isolated nucleic acid molecules, designated G2BD nucleic acid molecules, which encode the binding site from the gp78 ubiquitin ligase that binds to the Ube2G2 ubiquitin conjugating enzyme. The invention further provides isolated G2BD proteins and fusion proteins. Still further provided are diagnostic and therapeutic methods, as well as screening assays utilizing compositions of the invention.


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