The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2013
Filed:
Aug. 21, 2007
Nigel Gordon Smith, Norwich, GB;
Meredith Hans, Abington, PA (US);
Anthony M. Lowman, Wallingford, PA (US);
Andrea Jennifer Vernengo, Sicklerville, NJ (US);
Garland Fussell, Thorndale, PA (US);
Nigel Gordon Smith, Norwich, GB;
Meredith Hans, Abington, PA (US);
Anthony M. Lowman, Wallingford, PA (US);
Andrea Jennifer Vernengo, Sicklerville, NJ (US);
Garland Fussell, Thorndale, PA (US);
Synthes USA, LLC, West Chester, PA (US);
Drexel University, Philadelphia, PA (US);
Abstract
The present invention is directed to a bioadhesive thermogelling hydrogel composition for repairing and/or augmenting an intervertebral disc. The bioadhesive thermogelling hydrogel composition can be cross linked with the surrounding tissue so as to potentially serve as a nucleus pulposus replacement or augmentation along with serving to repair annular tears or fissure. The bioadhesive thermogelling hydrogel composition may include three main components: a thermal responsive polymer, an amine-containing polymer and a crosslinking component. All three components can be modified and combined in numerous ways to serve the need of the system as long as the amine-containing component is kept separate from the crosslinking component until the components are injected. The incorporation of a two-part crosslinking thermal responsive hydrogel permits smaller amounts of the crosslinking component to be used and enables the crosslinking dialdehyde to be delivered locally into the tissue that will react with the hydrogel. This helps prevent damage to tissues away from the hydrogel.