The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

Jul. 01, 2009
Applicants:

Kevin Wilson, West Newton, MA (US);

Gabriela DE Almeida, Brookline, MA (US);

Andrew Haidle, Cambridge, MA (US);

Kaleen Konrad, Newton, MA (US);

Michelle Machacek, Brookline, MA (US);

Ann Zabierek, Watertown, MA (US);

Inventors:

Kevin Wilson, West Newton, MA (US);

Gabriela de Almeida, Brookline, MA (US);

Andrew Haidle, Cambridge, MA (US);

Kaleen Konrad, Newton, MA (US);

Michelle Machacek, Brookline, MA (US);

Ann Zabierek, Watertown, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/38 (2006.01); C07D 333/36 (2006.01); C07D 333/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2). The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 and TYK2 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.


Find Patent Forward Citations

Loading…