The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2013
Filed:
Sep. 16, 2008
Jae Keol Rhee, Kyonggido, KR;
Weon Bin Im, Yongin-si, KR;
Chong Hwan Cho, Yongin-si, KR;
Sung Hak Choi, Seongnam-si, KR;
Tae Ho Lee, Yongin-si, KR;
Jae Keol Rhee, Kyonggido, KR;
Weon Bin Im, Yongin-si, KR;
Chong Hwan Cho, Yongin-si, KR;
Sung Hak Choi, Seongnam-si, KR;
Tae Ho Lee, Yongin-si, KR;
Dong-A Pharmaceuticals Co. Ltd., Seoul, KR;
Abstract
The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as, Staphylococci, Enterococci and Streptococci anaerobic microorganisms such asand Clostridia, and acid-resistant microorganisms such asand. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic.