The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

Jan. 30, 2009
Applicants:

Visweswara Akella Satya Surya Srinivas, Hyderabad, IN;

Ravikumar Tadiparthi, Aurangabad, IN;

Ganapavarapu Veera Raghava Sharma, Vishakhapatnam, IN;

Thirunavukkarasu Sappanimuthu, Chennai, IN;

Durairaj Peter Bhakiaraj, Chennai, IN;

Virendra Kachhadia, Chennai, IN;

Kilambi Narasimhan, Chennai, IN;

Sathya Narayana Thara, Chennai, IN;

Sriram Rajagopal, Bangalore, IN;

Sukunath Narayanan, Chennai, IN;

Venkatesan Parameswaran, Chennai, IN;

Venkatesan Janarthanam, Chennai, IN;

Maruthikumar Narayanam, Chennai, IN;

Sathyanarayana Gadde, Aurangabad, IN;

Uma Ramachandran, Chennai, IN;

Gopalan Balasubramanian, Chennai, IN;

Narayanan Surendran, Chennai, IN;

Shridhar Narayanan, Chennai, IN;

Lolaknath Santosh Vishwakarma, Chennai, IN;

Sanjeev Saxena, Chennai, IN;

Nishikanth Reddy Gaddam, Dublin, CA (US);

Inventors:

Visweswara Akella Satya Surya Srinivas, Hyderabad, IN;

Ravikumar Tadiparthi, Aurangabad, IN;

Ganapavarapu Veera Raghava Sharma, Vishakhapatnam, IN;

Thirunavukkarasu Sappanimuthu, Chennai, IN;

Durairaj Peter Bhakiaraj, Chennai, IN;

Virendra Kachhadia, Chennai, IN;

Kilambi Narasimhan, Chennai, IN;

Sathya Narayana Thara, Chennai, IN;

Sriram Rajagopal, Bangalore, IN;

Om Reddy Gaddam, Chennai, IN;

Sukunath Narayanan, Chennai, IN;

Venkatesan Parameswaran, Chennai, IN;

Venkatesan Janarthanam, Chennai, IN;

Maruthikumar Narayanam, Chennai, IN;

Sathyanarayana Gadde, Aurangabad, IN;

Uma Ramachandran, Chennai, IN;

Gopalan Balasubramanian, Chennai, IN;

Narayanan Surendran, Chennai, IN;

Shridhar Narayanan, Chennai, IN;

Lolaknath Santosh Vishwakarma, Chennai, IN;

Sanjeev Saxena, Chennai, IN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Described are novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. These compounds are useful in the treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; atherosclerosis; cancer; cachexia; ischemic-induced cell damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; ARDS; psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; asthma; COPD; bone resorption diseases; multiple sclerosis; sepsis; septic shock; toxic shock syndrome and fever. More particularly these compounds are useful as PDE4 inhibitors and are useful for treating PDE4 mediated diseases.


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