The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

Jan. 22, 2007
Applicants:

Kenneth Chien, Cambridge, MA (US);

Lisa Lesniewski, Boulder, CO (US);

Jerrold Olefsky, Solana Beach, CA (US);

Mohammad Pashmforoush, Los Angeles, CA (US);

Inventors:

Kenneth Chien, Cambridge, MA (US);

Lisa Lesniewski, Boulder, CO (US);

Jerrold Olefsky, Solana Beach, CA (US);

Mohammad Pashmforoush, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/11 (2006.01); A01N 63/00 (2006.01); C12N 15/00 (2006.01); C12N 5/00 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
Abstract

Provided are methods of treating insulin resistance or type II diabetes. Disrupting CAP in the macrophage can alter the inflammatory response associated with impaired insulin action and ultimately result in improved insulin action in target tissues. One aspect of the invention involves administering a CAP antagonist to a patient afflicted with insulin resistance or type II diabetes in an amount sufficient to improve insulin action in target tissues.


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