The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

Jul. 25, 2007
Applicants:

Richard Dana Kopke, Oklahoma City, OK (US);

Robert A. Floyd, Oklahoma City, OK (US);

Inventors:

Richard Dana Kopke, Oklahoma City, OK (US);

Robert A. Floyd, Oklahoma City, OK (US);

Assignee:

Oklahoma Medical Research Foundation, Oklahoma City, OK (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/06 (2006.01); A61K 31/15 (2006.01); A61K 31/195 (2006.01); A61K 38/00 (2006.01); A61K 31/41 (2006.01); A61P 27/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition includes compounds which function as free radical traps such as phenyl butyl nitrone (PBN), free radical scavengers, such as edaravone, resveratrol, ebselen and iron chelator and compounds from the family of antioxidant compounds including, but not limited to, N-acetylcysteine (NAC), Acetyl-L-Carnitine (ALCAR), glutathione monoethylester, ebselen, D-methionine and carbamathione. The compositions of the current invention may be delivered by injections or orally.


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