The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

Nov. 30, 2007
Applicants:

Anton Wellstein, Washington, DC (US);

Marcel O. Schmidt, Washington, DC (US);

Stephan Zbinden, Wabern, CH;

Mary Susan Burnett, Fairfax, VA (US);

Stephen E. Epstein, Rockville, MD (US);

Inventors:

Anton Wellstein, Washington, DC (US);

Marcel O. Schmidt, Washington, DC (US);

Stephan Zbinden, Wabern, CH;

Mary Susan Burnett, Fairfax, VA (US);

Stephen E. Epstein, Rockville, MD (US);

Assignees:

Georgetown University, Washington, DC (US);

MedStar Health Research Institute, Inc., Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61P 35/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Described herein are polypeptides that home to developing microvasculature, (also referred to as developing microvessels), such as newly developing microvasculature in mammals, particularly in humans, and to DNA that encodes such polypeptides. These polypeptides are referred to herein as developing microvasculature homing polypeptides. In a specific embodiment, the homing peptides are collateral vessel endothelia (CVE) homing polypeptides, which have been shown to home to collateral vessel endothelia after ischemia.


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