The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2013
Filed:
Aug. 27, 2010
Applicants:
George A. Oyler, Baltimore, MD (US);
Yung-nien Chang, Elkridge, MD (US);
Inventors:
George A. Oyler, Baltimore, MD (US);
Yung-Nien Chang, Elkridge, MD (US);
Assignee:
Synaptic Research, LLC, Baltimore, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/33 (2006.01); C12N 1/20 (2006.01); C12N 15/62 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
A novel protein delivery system to generate induced pluripotent stem (iPS) cells is described. The delivery system comprises a construct with a receptor binding domain that recognizes a receptor in a somatic cell, a translocation domain that allows the transfer of an inducer into the cytosolic space, and a cargo bearing domain to which the inducer is attached and facilitates transfer of the inducer into the cell.