The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

May. 17, 2011
Applicants:

Detlef Kozian, Kelkheim, DE;

Stefan Schaefer, Liederback, DE;

Bernward Schoelkens, Kelkheim, DE;

Karl-ernst Siegler, Ludwigshafen, DE;

Jean-francois Deleuze, Combs la Ville, FR;

Sylvain Ricard, Paris, FR;

Sandrine Mace, Jouy-En-Josas, FR;

Inventors:

Detlef Kozian, Kelkheim, DE;

Stefan Schaefer, Liederback, DE;

Bernward Schoelkens, Kelkheim, DE;

Karl-Ernst Siegler, Ludwigshafen, DE;

Jean-Francois Deleuze, Combs la Ville, FR;

Sylvain Ricard, Paris, FR;

Sandrine Mace, Jouy-En-Josas, FR;

Assignee:

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/48 (2006.01); G01N 33/68 (2006.01); C12P 13/08 (2006.01); C12P 13/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to a method identifying a risk for a thrombogenic disorder including, without limitation, atrial fibrillation, stroke, prolonged intermitted neurological deficit (PRIND), transitory ischemic attack (TIA), atherosclerotic cerebrovascular disease (CVD) and/or coronary heart disease, as well as to a method for selecting patients with a risk for a thrombogenic disorder, to a method for identifying a pharmaceutical for the therapy or prophylaxis of a thrombogenic disorder as well as to a method for producing a medicament and a diagnostic by employing the TAFI-Ile347 polymorphism.


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