The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2013

Filed:

Mar. 06, 2007
Applicants:

Langzhou Song, Freehold, NJ (US);

Valerian Nakaar, Hamden, CT (US);

Albert E. Price, New Haven, CT (US);

Lynda G. Tussey, Princeton, NJ (US);

James W. Huleatt, Brandford, CT (US);

Thomas J. Powell, Madison, CT (US);

Robert K. Evans, Souderton, PA (US);

Inventors:

Langzhou Song, Freehold, NJ (US);

Valerian Nakaar, Hamden, CT (US);

Albert E. Price, New Haven, CT (US);

Lynda G. Tussey, Princeton, NJ (US);

James W. Huleatt, Brandford, CT (US);

Thomas J. Powell, Madison, CT (US);

Robert K. Evans, Souderton, PA (US);

Assignee:

VaxInnate Corporation, Cranbury, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/295 (2006.01); A61K 39/145 (2006.01); C07K 19/00 (2006.01); C07K 14/11 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of making and compositions that stimulate a protective immune response in a subject include a portion of a protein from a naturally occurring viral hemagglutinin, wherein the protein portion includes at least a portion of a globular head and at least a portion of at least one secondary structure that causes the globular head to essentially retain its tertiary structure, and wherein the protein portion lacks a membrane fusion domain, a transmembrane domain and a cytoplasmic domain. Compositions can further include a Toll-like Receptor agonist and a carrier protein.


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