The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2013
Filed:
Feb. 21, 2006
Lea Eisenbach, Rechovot, IL;
Arthur Machlenkin, Kiryat-Ekron, IL;
Adrian Paz, Petach-Tikva, IL;
Boaz Tirosh, Brighton, MA (US);
Esther Tzehoval, Nes-Ziona, IL;
Lea Eisenbach, Rechovot, IL;
Arthur Machlenkin, Kiryat-Ekron, IL;
Adrian Paz, Petach-Tikva, IL;
Boaz Tirosh, Brighton, MA (US);
Esther Tzehoval, Nes-Ziona, IL;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Abstract
A method of inhibiting growth of, reducing or eliminating a cell population of a subject in need thereof is disclosed. The method comprises (a) thermally, mechanically and/or chemically damaging antigen-bearing cells which comprise at least one antigen characterizing cells of the cell population, with the proviso that the chemically damaging of the antigen-bearing cells is not predominantly effected using one or more antineoplastic agents, thereby generating immunogenic cells; and (b) introducing in the subject a cell aggregate which comprises the immunogenic cells and added antigen-presenting cells, thereby inducing an immune response for inhibiting growth of, reducing or eliminating the cell population of the subject.