The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2013

Filed:

Apr. 30, 2012
Applicants:

Anastasia Khvorova, Northborough, MA (US);

Devin Leake, Denver, CO (US);

Barbara Robertson, Boulder, CO (US);

Annaleen Vermeulen, Lafayette, CO (US);

Christina Yamada, Boulder, CO (US);

Inventors:

Anastasia Khvorova, Northborough, MA (US);

Devin Leake, Denver, CO (US);

Barbara Robertson, Boulder, CO (US);

Annaleen Vermeulen, Lafayette, CO (US);

Christina Yamada, Boulder, CO (US);

Assignee:

Dharmacon, Inc., Lafayette, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are methods of enhancing functionality of duplex oligonucleotides and compositions made by the methods. The duplex oligonucleotides include siRNAs, miRNA mimics, and piRNA mimics which contain modified nucleotides and mismatches between the two strands of the molecule at specific nucleotide positions.


Find Patent Forward Citations

Khvorova, Anastasia. (2013). Duplex oligonucleotides with enhanced functionality in gene regulation (U.S. Patent No. 8415466). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8415466

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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