The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2013

Filed:

Sep. 22, 2008
Applicants:

David John Haydon, Oxfordshire, GB;

Ian Collins, Oxfordshire, GB;

Lloyd George Czaplewski, Oxfordshire, GB;

Inventors:

David John Haydon, Oxfordshire, GB;

Ian Collins, Oxfordshire, GB;

Lloyd George Czaplewski, Oxfordshire, GB;

Assignee:

Biota Scientific Management Pty Ltd, Notting Hill, Victoria, AU;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/40 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula (IA) or (IB) have antibacterial activity: wherein W is ═C(H)— or ═N—; Ris a radical of formula -(Alk)-(Z)-(Alk)-Q wherein m, p and n are independently 0 or 1, provided that at least one of m, p and n is, Z1 is —O—, —S—, —S(O)—, —S(O)—, —NH—, —N(CH)—, —N(CHCH)—, —C(—O)—, —0—(C═O)—, —C(═O)—O—, or an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted divalent bicyclic carbocyclic or heterocyclic radical having 5 to 10 ring atoms; Alkand Alkare optionally substituted C-Calkylene, C-Calkenylene, or C-Calkynylene radicals, which may optionally terminate with or be interrupted by —O—, —S—, —S(O)—, —S(O)—, —NH—, —N(CH)—, Or —N(CHCH)—; and Q is hydrogen, halogen, nitrile, or hydroxyl, or an optionally substituted monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted bicyclic carbocyclic or heterocyclic radical having 5 to 10 ring atoms; Rand Rare optional substituents; and R, Rand Rare independently hydrogen or a radical of formula -(Alk)-(Z)y-(Alk)-H wherein x, y and z are independently 0 or 1, Zis —O—, —S—, —S(O)—, —S(O)—, —NH—, —N(CH)—, —N(CHCH)—, —C(—O)—, —0—(C═O)— or —C(═O)—O—; Alkand Alkare optionally substituted C-Calkylene, C-Calkenylene, or C-Calkynylene radicals, which may optionally terminate with or be interrupted by —O—, —S—, —S(O)—, —S(O)—, —NH—, —N(CH)—, or —N(CHCH)—.


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