The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2013
Filed:
Aug. 21, 2009
Applicants:
Christopher Thomas Brain, Cambridge, MA (US);
Moo Je Sung, Cambridge, MA (US);
Bharat Lagu, Acton, MA (US);
Inventors:
Christopher Thomas Brain, Cambridge, MA (US);
Moo Je Sung, Cambridge, MA (US);
Bharat Lagu, Acton, MA (US);
Assignees:
Novartis AG, Basel, CH;
Astex Therapeutics Ltd., Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/496 (2006.01); A61P 35/00 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to compounds of formula (I) and to pharmaceutically acceptable salts and pharmaceutical compositions thereof. The present invention also relates to use of the compounds of formula (I) in modulating the activity of protein kinases and in the treatment of disease, particularly a disease, disorder or syndrome associated with CDK 4 inhibition.