The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2013

Filed:

Jan. 19, 2012
Applicants:

Henning Steinhagen, Sulzbach, DE;

Bodo Scheiper, München, DE;

Hans Matter, Frankfurt am Main, DE;

Gary Mccort, Paris, FR;

Guillaume Begis, Paris, FR;

Pascale Goberville, Paris, FR;

Berangere Thiers, Paris, FR;

Inventors:

Henning Steinhagen, Sulzbach, DE;

Bodo Scheiper, München, DE;

Hans Matter, Frankfurt am Main, DE;

Gary McCort, Paris, FR;

Guillaume Begis, Paris, FR;

Pascale Goberville, Paris, FR;

Berangere Thiers, Paris, FR;

Assignee:

Sanofi, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/5025 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to cyclic indolizinecarboxamides and azaindolizinecarboxamides of the formulae Ia and Ib, wherein R, R, R, R, R, R, Y, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the formulae Ia and Ib, their use and pharmaceutical compositions comprising them.


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