The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2013
Filed:
Jun. 23, 2011
William V. Curran, Pear River, NY (US);
Christopher M. Liu, Somerville, MA (US);
Amy C. D. Bombardier, Waltham, MA (US);
Richard A. Leese, Suffern, NY (US);
You Seok Hwang, Concord, MA (US);
Blaise S. Lippa, Acton, MA (US);
Yanzhi Zhang, East Walpole, MA (US);
William V. Curran, Pear River, NY (US);
Christopher M. Liu, Somerville, MA (US);
Amy C. D. Bombardier, Waltham, MA (US);
Richard A. Leese, Suffern, NY (US);
You Seok Hwang, Concord, MA (US);
Blaise S. Lippa, Acton, MA (US);
Yanzhi Zhang, East Walpole, MA (US);
BioSource Pharm, Inc., Spring Valley, New York, NY (US);
Cubist Pharmaceuticals, Inc., Lexington, MA (US);
Abstract
Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds.