The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2013
Filed:
Apr. 11, 2007
Irun R. Cohen, Rehovot, IL;
Hila Amir-kroll, Gedera, IL;
Noam Cohen, Rishon le Zion, IL;
Gabriel Nussbaum, Jerusalem, IL;
Irun R. Cohen, Rehovot, IL;
Hila Amir-Kroll, Gedera, IL;
Noam Cohen, Rishon le Zion, IL;
Gabriel Nussbaum, Jerusalem, IL;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Abstract
The present invention provides improved vaccine compositions having enhanced immunogenicity and methods of using same. The compositions and methods include immunogenic conjugates containing peptide carriers derived from heat shock protein 60 (HSP60). The known synthetic peptide carrier, p458, provides significantly improved immunogenicity when provided as a multimeric conjugate comprising a plurality of peptide carrier units conjugated to each antigen. Cell vaccine compositions comprising antigen presenting cells loaded with multimeric p458 conjugates are also provided.