The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2013
Filed:
Dec. 23, 2008
Jean Rommelaere, Heidelberg, DE;
Zahari Raykov, Heidelberg, DE;
Joerg Schlehofer, Leimen, DE;
Irina Kiprijanova, Heidelberg, DE;
Tanja Heimberger, Würzburg, DE;
Assia Angelova, Sofia, BG;
Karsten Geletneky, Heidelberg, DE;
Marc Aprahamian, Heidelberg, DE;
Jean Rommelaere, Heidelberg, DE;
Zahari Raykov, Heidelberg, DE;
Joerg Schlehofer, Leimen, DE;
Irina Kiprijanova, Heidelberg, DE;
Tanja Heimberger, Würzburg, DE;
Assia Angelova, Sofia, BG;
Karsten Geletneky, Heidelberg, DE;
Marc Aprahamian, Heidelberg, DE;
Deutsches Krebsforschungszentrum, Heidelberg, DE;
Ruprecht-Karls-Universitaet Heidelberg, Heidelberg, DE;
Abstract
Described is a pharmaceutical composition containing (a) a parvovirus and (b) a chemotherapeutic agent, preferably as separate entities. The parvovirus might be based on parvovirus H1, LuIII, Mouse minute virus (MMV), Mouse parvovirus (MPV), Rat minute virus (RMV), Rat parvovirus (RPV), Rat virus (RV), vectors based on the foregoing viral species, and/or cells capable of actively producing the foregoing viral species. The pharmaceutical composition is beneficial for the treatment of a tumor. Tumors for which a parvovirus or the adjunction of the invention has particular utility include glioma, medulloblastoma, meningioma and pancreatic cancer. Preferred chemotherapeutic agents are gemcitabine and Temozolodine.