The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2013
Filed:
May. 14, 2012
Torsten Steinmetzer, Jena, DE;
Andrea Schweinitz, Jena, DE;
Joerg Stuerzebecher, Erfurt, DE;
Peter Steinmetzer, Jena, DE;
Anett Soeffing, Weimar, DE;
Andreas Van DE Locht, Munich, DE;
Silke Nicklisch, Leipzig, DE;
Claudia Reichelt, Leipzig, DE;
Friedrich-alexander Ludwig, Leipzig, DE;
Alexander Schulze, Grosstreben, DE;
Mohammed Daghish, Leipzig, DE;
Jochen Heinicke, Leipzig, DE;
Torsten Steinmetzer, Jena, DE;
Andrea Schweinitz, Jena, DE;
Joerg Stuerzebecher, Erfurt, DE;
Peter Steinmetzer, Jena, DE;
Anett Soeffing, Weimar, DE;
Andreas Van De Locht, Munich, DE;
Silke Nicklisch, Leipzig, DE;
Claudia Reichelt, Leipzig, DE;
Friedrich-Alexander Ludwig, Leipzig, DE;
Alexander Schulze, Grosstreben, DE;
Mohammed Daghish, Leipzig, DE;
Jochen Heinicke, Leipzig, DE;
The Medicines Company (Leipzig) GmbH, Leipzig, DE;
Abstract
The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrein, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of hyperfibrinolytic states, in organ transplants or heart surgery interventions, in particular with a cardiopulmonary bypass, or as a constituent of a fibrin adhesive.