The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2013
Filed:
Oct. 22, 2010
Zaihui Zhang, Vancouver, CA;
Timothy S Daynard, Vancouver, CA;
Shisen Wang, Coquitlam, CA;
Xinyao Du, Richmond, CA;
Gregory B Chopiuk, San Diego, CA (US);
Jun Yan, Coquitlam, CA;
Jianxin Chen, Vancouver, CA;
Serguei V Sviridov, Burnaby, CA;
Zaihui Zhang, Vancouver, CA;
Timothy S Daynard, Vancouver, CA;
Shisen Wang, Coquitlam, CA;
Xinyao Du, Richmond, CA;
Gregory B Chopiuk, San Diego, CA (US);
Jun Yan, Coquitlam, CA;
Jianxin Chen, Vancouver, CA;
Serguei V Sviridov, Burnaby, CA;
Dermira (Canada), Inc., Redwood City, CA (US);
Abstract
Pharmaceutical compositions and compounds are provided. The compounds of the invention have use as therapeutic agents, e.g., they demonstrate anti-proliferative, anti-inflammatory, anti-angiogenic, anti-migration activities. In one embodiment of the invention, formulations of the compounds in combination with a physiologically acceptable carrier are provided. The pharmaceutical formulations are useful in the treatment of, e.g., anti-inflammatory, renal, and hyperproliferative disorders. The compounds of the invention are pyrazolylbenzothiazole derivatives of the following formula (1) wherein X, R, R, Rand Rare described herein.