The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2013

Filed:

Nov. 03, 2009
Applicants:

Hugo Madden, Palo Alto, CA (US);

Greg Hemmi, Sunnyvale, CA (US);

Tarak Mody, Sunnyvale, CA (US);

Inventors:

Hugo Madden, Palo Alto, CA (US);

Greg Hemmi, Sunnyvale, CA (US);

Tarak Mody, Sunnyvale, CA (US);

Assignee:

Pharmacyclics, Inc., Sunnyvale, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 225/06 (2006.01); C07D 487/22 (2006.01); C07C 43/205 (2006.01); C07C 205/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed herein are the methods and compositions for the improved synthesis of texaphyrin metal complexes. The improved synthesis results in high-purity compositions of texaphyrin metal complexes in which more than about 98% of the texaphyrin metal complexes in the composition have the same structure and/or the same molecular weight. Further described herein are pharmaceutical compositions comprising such high-purity compositions, and the use of such high-purity compositions in the treatment of cancer and cardiovascular diseases and disorders.


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