The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2013

Filed:

Apr. 30, 2009
Applicants:

Anthony Calabro, Cleveland Heights, OH (US);

Aniq B. Darr, Piscataway, NJ (US);

Firouz Daneshgari, Akron, OH (US);

Inventors:

Anthony Calabro, Cleveland Heights, OH (US);

Aniq B. Darr, Piscataway, NJ (US);

Firouz Daneshgari, Akron, OH (US);

Assignee:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method is disclosed for treatment of urinary incontinence. The method includes the steps of providing to a person or animal, in the vicinity of a pubo-urethral ligament of the person or animal, a composition including collagen macromolecules that have hydroxyphenyl side groups substituted thereon, which are reacted to form dihydroxyphenyl linkages. In an embodiment, the collagen macromolecules are gelatin macromolecules. In another embodiment, the hydroxyphenyl side groups are tyramine side groups and the dihydroxyphenyl linkages are dityramine linkages. The composition can be injected into a space between a urethra and a pubis of the person or animal wherein the pubo-urethral ligament is disposed in the space. The method is advantageous, for example, based on being minimally invasive.


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