The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2013

Filed:

Dec. 26, 2010
Applicants:

Ehud Marom, Kfar Saba, IL;

Michael Mizhiritskii, Rehovot, IL;

Inventors:

Ehud Marom, Kfar Saba, IL;

Michael Mizhiritskii, Rehovot, IL;

Assignee:

Mapi Pharma Ltd., Ness Ziona, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/137 (2006.01); C07F 9/28 (2006.01); C07C 211/27 (2006.01); C07C 215/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses processes for the preparation of 3-[(1R,2R)-3-(dimethyl-amino)-1-ethyl-2-methyl-propyl]phenol (Tapentadol), salts thereof and related compounds of formula (A), including stereoisomers and pharmaceutically acceptable salts thereof, and to certain intermediates used in such process.


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