The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2013

Filed:

Jul. 30, 2012
Applicants:

Yoichi Takahashi, Osaka, JP;

Nobumasa Awai, Osaka, JP;

Hidenori Akatsuka, Osaka, JP;

Takayuki Kawaguchi, Osaka, JP;

Toru Iljima, Osaka, JP;

Inventors:

Yoichi Takahashi, Osaka, JP;

Nobumasa Awai, Osaka, JP;

Hidenori Akatsuka, Osaka, JP;

Takayuki Kawaguchi, Osaka, JP;

Toru Iljima, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 265/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Fused bicyclic compound having an affinity to mineral corticoid receptor (MR), of formula [I]: wherein ring A is benzene having a substituent R, fused to an adjacent 6-membered heterocyclic ring and further optionally having a substituent(s) other than R, Ris alkylsulfonylamino, etc., Rand Rare (a) the same of different and are hydrogen, alkyl, or optionally substituted aryl, or (b) combined with each other to form an oxo group or (c) combined with each other at its terminal together with the adjacent carbon atom to form cycloalkyl, X is ═N—, ═C(R)— or —CH(R)—, Ris (a) hydrogen, (b) cyano, (c) halogen, (d) alkyl, (e) alkenyl, (f) cycloalkyl, (g) alkanoyl, (h) carbamoyl, or (i) cycloalkenyl, Ar is an optionally substituted aromatic cyclic group and a dotted line means presence or absence of a double bond, or a pharmaceutically acceptable salt thereof, useful e.g. as an antihypertensive agent.


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