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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8410150 B1

PDFFull Text
Date of Patent:
Apr. 02, 2013

Filed:

Mar. 06, 2008

Inhibitors of carnitine palmitoyltransferase and treating cancer

Applicants:

Heinz W. Pauls, Oakville, CA;

Peter Brent Sampson, Oakville, CA;

Bryan T. Forrest, Toronto, CA;

Radoslaw Laufer, Oakville, CA;

Yong Liu, North York, CA;

Miklos Feher, Toronto, CA;

Yi Yao, Mississauga, CA;

Guohua Pan, Oakville, CA;

Inventors:

Heinz W. Pauls, Oakville, CA;

Peter Brent Sampson, Oakville, CA;

Bryan T. Forrest, Toronto, CA;

Radoslaw Laufer, Oakville, CA;

Yong Liu, North York, CA;

Miklos Feher, Toronto, CA;

Yi Yao, Mississauga, CA;

Guohua Pan, Oakville, CA;

Assignee:

University Health Network, Toronto, CA;

Attorneys:

McCarter & English, LLP

Steven G. Davis

Wei Song

Primary Examiner:

Michael Barker

Int. Cl.
CPC ...
C07D 307/66 (2006.01); C07D 333/32 (2006.01); C07D 213/18 (2006.01); C07D 233/70 (2006.01); C07D 417/04 (2006.01); C07D 263/36 (2006.01); C07D 249/12 (2006.01); C07D 261/10 (2006.01); C07D 207/36 (2006.01); C07D 275/03 (2006.01); C07D 271/06 (2006.01); C07D 285/08 (2006.01); C07C 335/16 (2006.01); C07C 327/40 (2006.01); C07C 327/08 (2006.01); C07C 311/10 (2006.01); C07C 237/14 (2006.01); A61K 31/34 (2006.01); A61K 31/381 (2006.01); A61K 31/4025 (2006.01); A61K 31/40 (2006.01); A61K 31/415 (2006.01); A61K 31/4164 (2006.01); A61K 31/4196 (2006.01); A61K 31/42 (2006.01); A61K 31/4245 (2006.01); A61K 31/425 (2006.01); A61K 31/433 (2006.01); A61K 31/435 (2006.01); A61K 31/64 (2006.01); A61K 31/155 (2006.01);
U.S. Cl.
CPC ...
Abstract

A CPT inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject having cancer comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

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