The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2013
Filed:
Apr. 09, 2010
Raphael Schiffmann, Rockwell, TX (US);
Teodoro G. Bottiglieri, Dallas, TX (US);
Erland Arning, Fort Worth, TX (US);
David F. Moore, Rockville, MD (US);
Raphael Schiffmann, Rockwell, TX (US);
Teodoro G. Bottiglieri, Dallas, TX (US);
Erland Arning, Fort Worth, TX (US);
David F. Moore, Rockville, MD (US);
Baylor Research Institute, Dallas, TX (US);
Abstract
Blood and tissue markers of the metabolic status, risk of health complications in Fabry disease patients and as a biomarker to follow the efficacy of treatment in animal models and patients with Fabry disease comprising tetrahydrobiopterin (BH4), precursors and metabolites of BH4, and other related co-factors is disclosed herein. The present invention further describes the use of BH4 therapy as a treatment option for Fabry disease to prevent, slow or reverses vascular cardiac and renal manifestations of Fabry disease.