The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2013

Filed:

Dec. 22, 2011
Applicants:

Alexandros Makriyannis, Watertown, MA (US);

Rajesh Thotapally, Pune, IN;

Venkata Kiran Rao Vemuri, Boston, MA (US);

Teresa Olszewska, Gdansk, PL;

Inventors:

Alexandros Makriyannis, Watertown, MA (US);

Rajesh Thotapally, Pune, IN;

Venkata Kiran Rao Vemuri, Boston, MA (US);

Teresa Olszewska, Gdansk, PL;

Assignee:

University of Connecticut, Farmington, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); A61K 31/405 (2006.01); C07D 207/00 (2006.01); C07D 209/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are biologically active hetero pyrrole analogs such as imidazoles, thiazoles, oxazoles and pyrazoles capable of interacting with the CB1 and/or the CB2 cannabinoid receptors. One aspect discloses hetero pyrrole analogs acting as antagonists for the CB1 and/or the CB2 receptors. Another aspect discloses hetero pyrrole analogs having selectivity for the CB1 or CB2 cannabinoid receptor. Also disclosed are pharmaceutical preparations employing the disclosed analogs and methods of administering therapeutically effective amounts of the disclosed analogs to provide a physiological effect.


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