The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2013

Filed:

Jan. 26, 2012
Applicants:

Akshay Vaishnaw, Arlington, MA (US);

Saraswathy V. Nochur, Newton, MA (US);

Sayda Elbashir, Cambridge, MA (US);

Muthiah Manoharan, Weston, MA (US);

Rachel Meyers, Newton, MA (US);

Inventors:

Akshay Vaishnaw, Arlington, MA (US);

Saraswathy V. Nochur, Newton, MA (US);

Sayda Elbashir, Cambridge, MA (US);

Muthiah Manoharan, Weston, MA (US);

Rachel Meyers, Newton, MA (US);

Assignee:

Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA comprises a sense strand of ALN-RSV01 and an antisense strand of ALN-RSV01.


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