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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8410057 B1

PDFFull Text
Date of Patent:
Apr. 02, 2013

Filed:

Dec. 29, 2009

Method of inducing t cell apoptosis by administering altered peptide ligand

Applicants:

Ariana Barbera Betancourt, Ciudad de la Habana, CU;

Maria Del Carmen Dominguez Horta, Ciudad de la Habana, CU;

Norailys Lorenzo Perez, Ciudad de la Habana, CU;

Gabriel Ramon Padron Palomares, Ciudad de La Hababa, CU;

Viviana Falcon Cama, Ciudad de La Habana, CU;

Ivon Menendez Valdes, Ciudad de la Habana, CU;

Inventors:

Ariana Barbera Betancourt, Ciudad de la Habana, CU;

Maria del Carmen Dominguez Horta, Ciudad de la Habana, CU;

Norailys Lorenzo Perez, Ciudad de la Habana, CU;

Gabriel Ramon Padron Palomares, Ciudad de La Hababa, CU;

Viviana Falcon Cama, Ciudad de La Habana, CU;

Ivon Menendez Valdes, Ciudad de la Habana, CU;

Assignee:

Centro de Ingenieria Genetica y Biotecnologia, Ciudad de la Habana, CU;

Attorney:

Hoffmann & Baron, LLP

Primary Examiner:

Robert Landsman

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61P 43/00 (2006.01); A61P 3/10 (2006.01); A61P 7/12 (2006.01); A61P 1/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is related with the field of the medicine, particularly with the use of an APL peptide or its analogues derived from the human heat shock protein of 60 kDa, for the manufacture of a pharmaceutical composition for the treatment of Crohn's disease, ulcerative colitis and diabetes mellitus type 1. This peptide is biodistributed into the gastrointestinal tract and also promotes the induction of apoptosis in activated intestinal lamina propria and peripheral blood T cells of patients with Crohn's disease. Furthermore, this peptide induces apoptosis in mononuclear cells of patients with diabetes mellitus type 1.

Find Patent Forward Citations

Barbera Betancourt, Ariana. (2013). Method of inducing t cell apoptosis by administering altered peptide ligand (U.S. Patent No. 8410057). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8410057

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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