The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2013
Filed:
Nov. 17, 2009
Marcia L. Macdonald, Vancouver, CA;
Mark E. Samuels, Vancouver, CA;
Robin Sherrington, North Vancouver, CA;
Yigal P. Goldberg, Vancouver, CA;
Marcia L. MacDonald, Vancouver, CA;
Mark E. Samuels, Vancouver, CA;
Robin Sherrington, North Vancouver, CA;
Yigal P. Goldberg, Vancouver, CA;
Xenon Pharmaceuticals Inc., Burnaby, B.C., CA;
Abstract
The present invention relates to the discovery that mutations in SCN9A are causative of Congenital Indifference to Pain (CIP) in humans. The invention also relates to methods of utilizing the SCN9A gene and expression products thereof for the screening and identification of therapeutic agents, including small organic compounds, which are selective for SCN9A, and are useful in the treatment of pain and other disorders. The invention also relates to methods of using these compounds to treat or otherwise ameliorate such disorders.