The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2013

Filed:

Nov. 25, 2008
Applicants:

Kyung-soo Hahm, Seoul, KR;

Yoonkyung Park, Jeollanam-do, KR;

Seong-cheol Park, Gwangju, KR;

Jong-kook Lee, Suncheon-si, KR;

Inventors:

Kyung-Soo Hahm, Seoul, KR;

Yoonkyung Park, Jeollanam-do, KR;

Seong-Cheol Park, Gwangju, KR;

Jong-Kook Lee, Suncheon-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/04 (2006.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a new antibiotic peptide and a usage thereof, which are derived from ribosomal protein L1, RPL1 of. Specifically, the antibiotic peptide comprising the amino acid sequence of SEQ. ID. NO:1 derived from ribosomal protein L1, RPL1 ofis substituted with a Phenylalanine, which is situated at the first and the eighth position from the antibiotic peptide, or in addition an Asparagine, which is situated at the thirteenth position of the antibiotic peptide, is substituted with lysine, wherein the produced peptides have maintained more decreased cytotoxicity when comparing to the existing antibiotic peptides and can be used as a safe antibiotics by showing more antibacterial activity.


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