The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2013
Filed:
Feb. 28, 2007
Jorge Roberto Toledo Alonso, Ciudad Habana, CU;
Oliberto Sánchez Ramos, Ciudad Habana, CU;
Maritza Isidra Barrera Valle, Ciudad de La Habana, CU;
Nancy Elena Figueroa Baile, Ciudad Habana, CU;
Yanet Prieto Carratala, La Habana, CU;
Maria Pilar Rodriguez Molto, Cuidad de La Habana, CU;
Maria Teresa Frias Lepoureau, Ciudad de La Habana, CU;
Carlos Guillermo Borroto Nordelo, Ciudad Habana, CU;
Jorge Roberto Toledo Alonso, Ciudad Habana, CU;
Oliberto Sánchez Ramos, Ciudad Habana, CU;
Maritza Isidra Barrera Valle, Ciudad de La Habana, CU;
Nancy Elena Figueroa Baile, Ciudad Habana, CU;
Yanet Prieto Carratala, La Habana, CU;
Maria Pilar Rodriguez Molto, Cuidad de La Habana, CU;
Maria Teresa Frias Lepoureau, Ciudad de La Habana, CU;
Carlos Guillermo Borroto Nordelo, Ciudad Habana, CU;
Centro de Ingenieria Genetica y Biotecnologia, Ciudad de La Habana, CU;
Centro Nacional de Sanidad Agropecuaria, La Habana, CU;
Abstract
The current invention describes chimeric vaccine antigens against the virus that causes the Classic Swine Fever (CSFV). Such vaccine antigens are based on viral subunits coupled to proteins able to stimulate cellular and humoral immune system. Chimeric antigens can be produced in expression systems that guarantee a correct tertiary structure folding of the chimeric molecules, which constitute the essence of the current invention. The vaccine formulations containing such chimeric antigens induce an early and potent immune response on vaccinated pigs and confer full protection against CSFV. Moreover, the resultant vaccine formulations prevent the viral transmission from sows to their offspring. The chimeric antigens, as well as the resultant vaccine formulations, can be applied in animal health as vaccines for preventive use in swine.