The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2013
Filed:
Nov. 14, 2008
Thomas J. Tucker, North Wales, PA (US);
Robert Tynebor, Hatfield, PA (US);
John T. Sisko, Lansdale, PA (US);
Neville Anthony, Chalfont, PA (US);
Robert Gomez, Perkasie, PA (US);
Samson M. Jolly, Collegeville, PA (US);
Thomas J. Tucker, North Wales, PA (US);
Robert Tynebor, Hatfield, PA (US);
John T. Sisko, Lansdale, PA (US);
Neville Anthony, Chalfont, PA (US);
Robert Gomez, Perkasie, PA (US);
Samson M. Jolly, Collegeville, PA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Heteroaromatic compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein ring A is: (ii-a), (ii-b), (ii-c), (ii-d), or (ii-e); and wherein n, L, M, U, X, Y, Z, R, R, R, R, R, R, R, R, Rand Rare defined herein. The compounds of Formula I and their pharmaceutically acceptable salts and prodrugs are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts and prodrugs can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.