The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2013
Filed:
Dec. 07, 2007
Uma Sinha, San Francisco, CA (US);
Stanley J. Hollenbach, South San Francisco, CA (US);
Keith Abe, South San Francisco, CA (US);
Uma Sinha, San Francisco, CA (US);
Stanley J. Hollenbach, South San Francisco, CA (US);
Keith Abe, South San Francisco, CA (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
Unit doses of factor Xa inhibitor compounds and methods of using these compounds for inhibiting blood coagulation in a human patient are taught herein. The unit dose of the factor Xa inhibitor compounds disclosed herein required to inhibit coagulation in a primate is lower than the unit dose required to obtain similar levels of coagulation inhibition in other animal models, such as rodents. Also taught are in vitro assays useful in predicting in vivo antithrombotic activity in humans.