The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2013

Filed:

Nov. 03, 2010
Applicants:

Jean Ferand Armand Lacrampe, Le Mesnil-Esnard, FR;

Christophe Meyer, Les Authieux sur le Port Saint Ouen, FR;

Yannick Aimè Eddy Ligny, Sotteville-lès-Rouen, FR;

Imre Christian Francis Csoka, Louviers, FR;

Luc Van Hijfte, Belbeuf, FR;

Janine Arts, Breda, NL;

Bruno Schoentjes, Bois-Guillaume, FR;

Camille Georges Wermuth, Strasbourg, FR;

Bruno Giethlen, Altorf, FR;

Jean-marie Contreras, Benfeld, FR;

Muriel Joubert, Illkirch, FR;

Inventors:

Jean Ferand Armand Lacrampe, Le Mesnil-Esnard, FR;

Christophe Meyer, Les Authieux sur le Port Saint Ouen, FR;

Yannick Aimè Eddy Ligny, Sotteville-lès-Rouen, FR;

Imre Christian Francis Csoka, Louviers, FR;

Luc Van Hijfte, Belbeuf, FR;

Janine Arts, Breda, NL;

Bruno Schoentjes, Bois-Guillaume, FR;

Camille Georges Wermuth, Strasbourg, FR;

Bruno Giethlen, Altorf, FR;

Jean-Marie Contreras, Benfeld, FR;

Muriel Joubert, Illkirch, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/4709 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, s, t, R, R, R, R, R, R, R, X, Y, Q and Z have defined meanings.


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