The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8404679 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 26, 2013

Filed:

Apr. 23, 2012
Applicants:

Caterina Bissantz, Village-Neuf, FR;

Philippe Jablonski, Steinbrunn-le-Haut, FR;

Henner Knust, Rheinfelden, DE;

Andreas Koblet, Bottmingen, CH;

Anja Limberg, Basel, CH;

Matthias Nettekoven, Grenzach-Wyhlen, DE;

Hasane Ratni, Habsheim, FR;

Claus Riemer, Freiburg, DE;

Inventors:

Caterina Bissantz, Village-Neuf, FR;

Philippe Jablonski, Steinbrunn-le-Haut, FR;

Henner Knust, Rheinfelden, DE;

Andreas Koblet, Bottmingen, CH;

Anja Limberg, Basel, CH;

Matthias Nettekoven, Grenzach-Wyhlen, DE;

Hasane Ratni, Habsheim, FR;

Claus Riemer, Freiburg, DE;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/498 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); C07D 207/14 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 417/06 (2006.01); A61K 31/454 (2006.01); A61K 31/501 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 405/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds of formula I wherein R, R, R, Ar and n are as defined herein and pharmaceutically active salts, racemic mixtures, enantiomers, optical isomers or tautomeric forms thereof. The compounds can be used for the treatment of depression, anxiety or schizophrenia.


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