The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2013
Filed:
Oct. 29, 2010
Hong Woo Kim, Cambridge, MA (US);
Jong Sung Koh, Seoul, KR;
Jaekyoo Lee, North Andover, MA (US);
Ho-juhn Song, Andover, MA (US);
Youngsam Kim, Seoul, KR;
Hee Kyu Lee, Gunpo Si, KR;
Jang-sik Choi, Cheonan-si, KR;
Sun-hee Lim, Cheonan-si, KR;
Sunhwa Chang, Cheonan-si, KR;
Hong Woo Kim, Cambridge, MA (US);
Jong Sung Koh, Seoul, KR;
Jaekyoo Lee, North Andover, MA (US);
Ho-Juhn Song, Andover, MA (US);
Youngsam Kim, Seoul, KR;
Hee Kyu Lee, Gunpo Si, KR;
Jang-Sik Choi, Cheonan-si, KR;
Sun-Hee Lim, Cheonan-si, KR;
Sunhwa Chang, Cheonan-si, KR;
Genosco, Buena Park, CA (US);
Oscotec, Inc., Cheonan, KR;
Abstract
The present invention provides a new group of protein kinase inhibitors, pyrido[4,3,-d]pyrimidin-5-one derivatives, and pharmaceutically acceptable salts thereof that are useful for intreating cell proliferative disease and disorder such as cancer, autoimmune diseases, infection, cardiovascular disease and neurodegenerative disease and disorder. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor. The invention also provides useful intermediates generated during the syntheses of the pyrido[4,3,-d]pyrimidin-5-one derivatives.