The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2013

Filed:

Sep. 29, 2011
Applicants:

Milan Chytil, Clinton, MA (US);

Sharon R. Engel, Hudson, MA (US);

Qun Kevin Fang, Wellesley, MA (US);

Kerry L. Spear, Concord, MA (US);

Inventors:

Milan Chytil, Clinton, MA (US);

Sharon R. Engel, Hudson, MA (US);

Qun Kevin Fang, Wellesley, MA (US);

Kerry L. Spear, Concord, MA (US);

Assignee:

Sunovion Pharmaceuticals Inc., Marlborough, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/33 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.


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